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Research on related factors for hypoglycemic episodes in patients with type 2 diabetes mellitus based on continuous glucose monitoring system
ZHANG Ya-wen, ZHANG Qiong-yue, TAO Jun-jun, MIAO Qing, ZENG Fang-fang, ZHOU Li-nuo, YANG Ye-hong
jms, 2021, 48(05): 637-647.   DOI: 10.3969/j.issn.1672-8467.2021.05.011

Variables r P
  FPG: Fasting plasma glucose; PPG: Postprandial plasma glucose; HbA1c: Glycated hemoglobin; BMI: Body mass index; BUN: Blood urea nitrogen; eGFR: Estimated glomerular filtration rate; MBG: Mean blood glucose; SD: Standard deviation; CV: Coefficient of variance; ΔBG: The difference between the highest and lowest blood glucose; MAGE: Mean amplitude of glycemic excursions; %TIR: The percentage of time in range.
Baseline variables
Gender 0.093 0.518
Age -0.050 0.725
BMI -0.092 0.530
Microvascular complications 0.016 0.914
Combined hypertension -0.249 0.077
Duration of hypertension -0.112 0.455
Insulin secretagogues 0.219 0.123
Sulfonylureas 0.344 0.013(1)
Glinides -0.097 0.498
Metformin -0.067 0.642
α-glucosidase inhibitors -0.031 0.827
Sodium-dependent glucose transporters 2 inhibitors -0.078 0.585
Glucagon like peptide-1 receptor agonists -0.160 0.263
Dipeptidy1 peptidase-4 inhibitors -0.123 0.391
Insulin treatment -0.147 0.304
FPG 0.072 0.616
PPG 0.177 0.219
Fasting plasma insulin 0.072 0.616
Postprandial plasma insulin 0.177 0.219
Fasting plasma C peptide 0.038 0.795
Postprandial plasma C peptide 0.047 0.745
HbA1c -0.221 0.119
BUN 0.004 0.978
eGFR -0.102 0.484
CGM parameters
  MBG -0.219 0.123
  SD 0.205 0.149
  CV 0.428 0.002(2)
  ΔBG 0.129 0.366
  MAGE 0.250 0.077
%TIR (mmol/L)
  3.9-7.8 0.002 0.989
   > 7.8 -0.173 0.223
  3.9-10.0 -0.242 0.087
   > 10.0m -0.030 0.833
4 Associations between variables and duration of hypoglycemic episodes  (n=57)
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