Fudan University Journal of Medical Sciences

Research on related factors for hypoglycemic episodes in patients with type 2 diabetes mellitus based on continuous glucose monitoring system

ZHANG Ya-wen, ZHANG Qiong-yue, TAO Jun-jun, MIAO Qing, ZENG Fang-fang, ZHOU Li-nuo, YANG Ye-hong

jms, 2021, 48(05): 637-647. DOI: 10.3969/j.issn.1672-8467.2021.05.011

Variables	Univariate Logistic regression		Model 1		Model 2
Variables	OR (95%CI)	P	OR (95%CI)	P	OR (95%CI)	P
OR: Odds ratio; CI: Confidence interval; HbA1c: Glycated hemoglobin; BUN: Blood urea nitrogen; BMI: Body mass index; FPG: Fasting plasma glucose; PPG: Postprandial plasma glucose; eGFR: Estimated glomerular filtration rate. Model 1:Adjusted for FPG, PPG, fasting plasma C peptide, BUN, eGFR, combined hypertension, insulin treatment, MBG. Model 2:Adjusted for gender, age, BMI, FPG, PPG, fasting plasma C peptide, BUN, eGFR, combined hypertension, insulin treatment, MBG.
Gender	0.941 (0.478-1.853)	0.860	-	-	1.140 (0.426-3.053)	0.794
Age	0.983 (0.953-1.013)	0.259	-	-	0.963 (0.918-1.011)	0.126
BMI	0.989 (0.912-1.072)	0.792	-	-	1.049 (0.930-1.183)	0.435
FPG	0.810 (0.709-0.926)	0.002⁽²⁾	0.851 (0.695-1.042)	0.119	0.848 (0.689-1.043)	0.119
PPG	0.926 (0.848-1.012)	0.088	1.051 (0.915-1.208)	0.479	1.050 (0.912-1.210)	0.497
Fasting plasma C peptide	0.933 (0.803-1.083)	0.360	1.004 (0.812-1.242)	0.967	0.936 (0.743-1.179)	0.573
BUN	0.984 (0.893-1.085)	0.749	0.744 (0.575-0.963)	0.025⁽¹⁾	0.798 (0.609-1.046)	0.102
eGFR	1.002 (0.991-1.013)	0.750	0.978 (0.957-1.000)	0.055	0.973 (0.950-0.997)	0.026⁽¹⁾
Combined hypertension	2.265 (1.151-4.456)	0.018⁽¹⁾	0.520 (0.209-1.295)	0.160	0.513 (0.192-1.373)	0.184
Insulin treatment	2.251 (1.115-4.541)	0.024⁽¹⁾	5.549 (2.047-15.041)	0.001⁽²⁾	5.732 (2.017-16.295)	0.001⁽²⁾
MBG	0.564 (0.429-0.740)	< 0.001⁽³⁾	0.573 (0.411-0.798)	0.001⁽²⁾	0.579 (0.413-0.811)	0.002⁽²⁾

5 Results of Logistic regression analysis to related factors for hypoglycemic episodes (n=147)

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