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Research on related factors for hypoglycemic episodes in patients with type 2 diabetes mellitus based on continuous glucose monitoring system
ZHANG Ya-wen, ZHANG Qiong-yue, TAO Jun-jun, MIAO Qing, ZENG Fang-fang, ZHOU Li-nuo, YANG Ye-hong
jms, 2021, 48(05): 637-647.   DOI: 10.3969/j.issn.1672-8467.2021.05.011

Variables r P
  FPG: Fasting plasma glucose; PPG: Postprandial plasma glucose; HbA1c: Glycated hemoglobin; BMI: Body mass index; BUN: Blood urea nitrogen; eGFR: Estimated glomerular filtration rate; MBG: Mean blood glucose; SD: Standard deviation; CV: Coefficient of variance; ΔBG: The difference between the highest and lowest blood glucose; MAGE: Mean amplitude of glycemic excursions; %TIR: The percentage of time in range.
Baseline variables
Gender -0.015 0.861
Age -0.091 0.272
BMI -0.015 0.865
Microvascular complications 0.074 0.376
Combined hypertension -0.197 0.017(1)
Duration of hypertension -0.166 0.050
Insulin secretagogues -0.127 0.125
Sulfonylureas -0.057 0.494
Glinides -0.116 0.164
Metformin -0.002 0.983
Glitazones -0.145 0.080
α-glucosidase inhibitors -0.017 0.392
Sodium-dependent glucose transporters 2
inhibitors
-0.020 0.806
Glucagon like peptide-1 receptor agonists 0.084 0.310
Dipeptidy1 peptidase-4 inhibitors -0.002 0.982
Insulin treatment 0.189 0.022(1)
FPG -0.321 < 0.001(3)
PPG -0.189 0.030(1)
Fasting plasma insulin -0.123 0.157
Postprandial plasma insulin -0.010 0.908
Fasting plasma C peptide -0.234 0.006(2)
Postprandial plasma C peptide -0.113 0.195
HbA1c -0.056 0.532
BUN -0.202 0.017(1)
eGFR 0.009 0.916
CGM parameters
  MBG -0.382 < 0.001(3)
  SD 0.236 0.004(2)
  CV 0.500 < 0.001(3)
  ΔBG 0.355 < 0.001(3)
  MAGE 0.169 0.042(1)
%TIR (mmol/L)
  3.9-7.8 0.263 0.001(2)
   > 7.8 -0.336 < 0.001(3)
  3.9-10.0 0.095 0.252
   > 10.0 -0.196 0.017(1)
3 Associations between variables and hypoglycemic episodes  (n=147)
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