Advancement in the study of relations of autophagy, carcinogenesis and cancer therapy

WANG Shu-yan△;ZHOU Yi-ming;CHEN Zong-you

Fudan University Journal of Medical Sciences ›› 2008, Vol. 35 ›› Issue (6) : 928-0.

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Fudan University Journal of Medical Sciences ›› 2008, Vol. 35 ›› Issue (6) : 928-0.
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Advancement in the study of relations of autophagy, carcinogenesis and cancer therapy

  • LIU Ming, SUN Ai-yun, GE Jun-bo
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Abstract

objective Dendritic cells are the most potent antigen-presenting cell which play a critical role in the process of identifying antigen and promoting T-cell reponses. Dendritic cell migration is the prerequisite of optimal immune response and these two functions are integrated into each other. The recruitment of blood dendritic cells to the peripheral tissue and secondary lymphoid organs are regulated by chemokines and chemokine receptors, adhesion molecules, and matrix-degrading metalloproteinases. The proper localization of dendritic cells facilitates the innate and adaptive immunity.

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autophagy / apoptosis / carcinogenesis / cancer therapy

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LIU Ming;SUN Ai-yun;GE Jun-bo�. Mechanisms of dendritic cell adhesion, chemotaxis, and migration[J]. Fudan University Journal of Medical Sciences, 2008, 35(6): 928-0
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