目的 比较4种成人Still病(adult onset Still’s disease,AOSD)诊断标准的诊断效率。方法 研究对象为2003年1月至2009年12月复旦大学附属中山医院诊断的AOSD患者70例,以同期发热患者140例为对照。收集临床资料,分析敏感度、特异度和准确率。结果 4种诊断标准均有较高的特异度,其中以ARA标准的特异度最高(99.3%),准确率为83.3%。敏感度以Yamaguchi标准最高(78.6%),准确率87.1%。结论 Yamaguchi标准用于目前临床诊断较为合适。
Objective To verificate and evaluate four different diagnostic criteria of adult onset Still’s disease (AOSD). Methods Seventy AOSD patients admitted in Zhongshan Hospital afflicated Fudan University from Jan. 2003 to Dec. 2009 were enrolled. Another 140 non-AOSD patients with fever were selected as the control. Four different diagnostic criteria (Calabro, ARA, Cush and Yamaguchi) of AOSD were applied to all patients. Results The specificities of four different classification criteria were all high. The sensitivity (78.6%) and accuracy (87.1%) of Yamaguchi criteria were the highest. The specificity of ARA criteria was the highest (99.3%), so was its accuracy (83.3%). Conclusions It is appropriate to use Yamaguchi criteria for diagnosis of AOSD at present.