中图分类号:
R563
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参考文献
[1] VESTBO J, HURD SS, AGUSTÍ AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary[J]. Am J Respir Crit Care Med, 2013, 187(4): 347-365.
[2] SUN X, FENG X, ZHENG D, et al. Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo[J]. Clin Sci (Lond), 2019, 133(13): 1523-1536.
[3] CHOWHAN RK, RAHAMAN H, SINGH LR. Structural basis of peroxidase catalytic cycle of human Prdx6[J]. Sci Rep, 2020, 10(1): 17416.
[4] RUSHEFSKI M, APLENC R, MEYER N, et al. Novel variants in the PRDX6 Gene and the risk of acute lung injury following major trauma[J]. BMC Med Genet, 2011, 12: 77.
[5] VÁZQUEZ-MEDINA JP, TAO JQ, PATEL P, et al. Genetic inactivation of the phospholipase A 2 activity of peroxiredoxin 6 in mice protects against LPS-induced acute lung injury[J]. Am J Physiol Lung Cell Mol Physiol, 2019, 316(4): L656-L668.
[6] 中华医学会呼吸病学分会肺功能专业组. 肺功能检查指南(2)[J]. 中华结核和呼吸杂志, 2014-2015, 37(7): 481-485.
[7] BEN ANES A, FETOUI H, BCHIR S, et al. Increased oxidative stress and altered levels of nitric oxide and peroxynitrite in tunisian patients withchronic obstructive pulmonary disease: correlation with disease severity and airflow obstruction[J]. Biol Trace Elem Res, 2014, 161(1): 20-31.
[8] TAN WSD, SHEN HM, WONG WSF. Dysregulated autophagy in COPD: a pathogenic process to be deciphered[J]. Pharmacol Res, 2019, 144: 1-7.
[9] LIEN YC, FEINSTEIN SI, DODIA C, et al. The roles of peroxidase and phospholipase A2 activities of peroxiredoxin 6 in protecting pulmonary microvascular endothelial cells against peroxidative stress[J]. Antioxid Redox Signal, 2012, 16(5): 440-451.
[10] LÓPEZ-GRUESO MJ, LAGAL DJ, GARCÍA-JIMÉNEZ ÁF, et al. Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells[J]. Redox Biol, 2020, 37: 101737.
[11] SCHATTAUER SS, BEDINI A, SUMMERS F, et al. Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation[J]. J Biol Chem, 2019, 294(45): 16884-16896.
[12] CHHUNCHHA B, KUBO E, SINGH P, et al. Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress[J]. Aging (Albany NY), 2018, 10(9): 2284-2315.
[13] KIM SY, JO HY, KIM MH, et al. H2O2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via up-regulation of iPLA2 activity[J]. J Biol Chem, 2008, 283(48): 33563-33568.
[14] VUONG NQ, GOEGAN P, DE ROSE F, et al. Responses of A549 human lung epithelial cells to cristobalite and α-quartz exposures assessed by toxicoproteomics and gene expression analysis[J]. J Appl Toxicol, 2017, 37(6): 721-731.
[15] 刘谦, 袁晟, 刘勇. 弥漫大B细胞淋巴瘤中Prdx6的表达及其预后意义[J]. 临床与实验病理学杂志, 2021, 37(3): 279-283.
[16] 辛亮, 李鸣, 韩敏, 等. Prdx6在缺血缺氧状态下对肝细胞的保护作用及其机制[J]. 广东医学, 2017, 38(20): 3082-3087.
[17] HU X, LU E, PAN C, et al. Overexpression and biological function of PRDX6 in human cervical cancer[J]. J Cancer, 2020, 11(9): 2390-2400.
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脚注
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基金
上海市自然科学基金(20Z11901004);上海市浦东新区科技发展基金事业单位民生科研专项(PKJ2021-Y35);上海市浦东医院学科建设推进工程(Zdzk2020-11)
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